Clinical trials of pig kidney transplants to humans could start as early as 2028 in two specific hospitals in Japan, according to a news report by Kyodo News. This one-of-a-kind development, if successful, could help Japan address the shortage of organ donors.
It should be recalled that a recipient of a pig kidney in the United States survived a record-breaking 271 days before the organ had to be removed. Over a hundred thousand people in America are currently waiting for organ transplants and most of them in need of kidneys.
To put things in perspective, posted below is an excerpt from the report of Kyodo News. Some parts in boldface…
A Japanese startup said Monday it will conduct clinical trials of pig kidney transplants to humans at two hospitals as early as 2028, which if successful would likely make them the first of their kind in the country.
It is hoped that organ transplants from pigs to humans will address the shortage of organ donors in Japan. Pig kidney transplants have previously been carried out on a trial basis in the United States and China.
According to the Meiji University venture, PorMedTec, the kidneys, which have been genetically modified to prevent organ rejection, will be transplanted at Hokkaido University Hospital in Sapporo and Shonan Kamakura General Hospital in Kamakura, Kanagawa Prefecture.
“We want to lay the foundation of xenotransplantation in Japan,” Hiroshi Nagashima, a Meiji University professor and representative director of the company, said in a press release, referring to the surgical transfer of non-human animals’ organs to human recipients.
The startup imports genetically modified pig cells developed by U.S. biotechnology company eGenesis Inc. and produces pigs with the same features in Japan. The genes of the animal have been modified in 69 areas to prevent organs from being rejected by recipients’ bodies.
The Japanese firm said it will finalize plans for the clinical trial and hopes to promote the widespread use of the treatment for patients with severe kidney failure once manufacturing and marketing approval is granted.
Let me end this piece by asking you readers: What is your reaction to this development? What is the first thing you think of when it comes to transplanting animal organs into human bodies? Are you concerned that kidneys from pigs are not 100% compatible with humans? How many members of your local community suffer from kidney-related problems?
You may answer in the comments below. If you prefer to answer privately, you may do so by sending me a direct message online.
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